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Page 1
Metabolic reprogramming and altered cell envelope characteristics in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibiotics.
Zeden MS, Gallagher LA, Bueno E, Nolan AC, Ahn J, Shinde D, Razvi F, Sladek M, Burke Ó, O'Neill E, Fey PD, Cava F, Thomas VC, O'Gara JP. Zeden MS, et al. Among authors: gallagher la. PLoS Pathog. 2023 Jul 24;19(7):e1011536. doi: 10.1371/journal.ppat.1011536. eCollection 2023 Jul. PLoS Pathog. 2023. PMID: 37486930 Free PMC article.
The Novel Membrane-Associated Auxiliary Factors AuxA and AuxB Modulate β-lactam Resistance in MRSA by stabilizing Lipoteichoic Acids.
Mikkelsen K, Sirisarn W, Alharbi O, Alharbi M, Liu H, Nøhr-Meldgaard K, Mayer K, Vestergaard M, Gallagher LA, Derrick JP, McBain AJ, Biboy J, Vollmer W, O'Gara JP, Grunert T, Ingmer H, Xia G. Mikkelsen K, et al. Among authors: gallagher la. Int J Antimicrob Agents. 2021 Mar;57(3):106283. doi: 10.1016/j.ijantimicag.2021.106283. Epub 2021 Jan 24. Int J Antimicrob Agents. 2021. PMID: 33503451 Free article.
Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant Staphylococcus aureus (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics.
Campbell C, Fingleton C, Zeden MS, Bueno E, Gallagher LA, Shinde D, Ahn J, Olson HM, Fillmore TL, Adkins JN, Razvi F, Bayles KW, Fey PD, Thomas VC, Cava F, Clair GC, O'Gara JP. Campbell C, et al. Among authors: gallagher la. mBio. 2021 Jun 29;12(3):e0053021. doi: 10.1128/mBio.00530-21. Epub 2021 Jun 29. mBio. 2021. PMID: 34182779 Free PMC article.
Metabolic reprogramming and flux to cell envelope precursors in a pentose phosphate pathway mutant increases MRSA resistance to β-lactam antibiotics.
Zeden MS, Gallagher LA, Bueno E, Nolan AC, Ahn J, Shinde D, Razvi F, Sladek M, Burke Ó, O'Neill E, Fey PD, Cava F, Thomas VC, O'Gara JP. Zeden MS, et al. Among authors: gallagher la. bioRxiv [Preprint]. 2023 Mar 7:2023.03.03.530734. doi: 10.1101/2023.03.03.530734. bioRxiv. 2023. PMID: 36945400 Free PMC article. Updated. Preprint.
Tandem Amplification of the Staphylococcal Cassette Chromosome mec Element Can Drive High-Level Methicillin Resistance in Methicillin-Resistant Staphylococcus aureus.
Gallagher LA, Coughlan S, Black NS, Lalor P, Waters EM, Wee B, Watson M, Downing T, Fitzgerald JR, Fleming GTA, O'Gara JP. Gallagher LA, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00869-17. doi: 10.1128/AAC.00869-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28717043 Free PMC article.